6drs
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Dihydrofolate Reductase (DHFR) of Aspergillus flavus in complex with a small molecule inhibitor== | |
- | + | <StructureSection load='6drs' size='340' side='right'caption='[[6drs]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6drs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_flavus_NRRL3357 Aspergillus flavus NRRL3357]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DRS FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.997Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H8A:3-{[(3R)-7,9-diamino-3-methyl-2,3-dihydrofuro[2,3-f]quinazolin-4-yl]oxy}benzonitrile'>H8A</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
- | [[Category: Akers-Rodriguez | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6drs OCA], [https://pdbe.org/6drs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6drs RCSB], [https://www.ebi.ac.uk/pdbsum/6drs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6drs ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: Fortier | + | == Function == |
- | [[Category: | + | [https://www.uniprot.org/uniprot/B8NBN5_ASPFN B8NBN5_ASPFN] |
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Aspergillus flavus NRRL3357]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Akers-Rodriguez S]] | ||
+ | [[Category: Bensen DC]] | ||
+ | [[Category: Fortier JM]] | ||
+ | [[Category: Tari LW]] |
Current revision
Dihydrofolate Reductase (DHFR) of Aspergillus flavus in complex with a small molecule inhibitor
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