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6dvo

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==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with Bavarostat==
==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with Bavarostat==
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<StructureSection load='6dvo' size='340' side='right' caption='[[6dvo]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
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<StructureSection load='6dvo' size='340' side='right'caption='[[6dvo]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6dvo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DVO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DVO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6dvo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DVO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HBV:3-fluoro-N-hydroxy-4-[(methyl{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]methyl}amino)methyl]benzamide'>HBV</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hdac6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HBV:3-fluoro-N-hydroxy-4-[(methyl{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]methyl}amino)methyl]benzamide'>HBV</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dvo OCA], [http://pdbe.org/6dvo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dvo RCSB], [http://www.ebi.ac.uk/pdbsum/6dvo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dvo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dvo OCA], [https://pdbe.org/6dvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dvo RCSB], [https://www.ebi.ac.uk/pdbsum/6dvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dvo ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/F8W4B7_DANRE F8W4B7_DANRE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6dvo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6dvo" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brachidanio rerio]]
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[[Category: Danio rerio]]
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[[Category: Christianson, D W]]
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[[Category: Large Structures]]
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[[Category: Porter, N J]]
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[[Category: Christianson DW]]
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[[Category: Histone deacetylase]]
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[[Category: Porter NJ]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Metallohydrolase]]
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Current revision

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with Bavarostat

PDB ID 6dvo

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