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6e35
From Proteopedia
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==Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160== | ==Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160== | ||
| - | <StructureSection load='6e35' size='340' side='right' caption='[[6e35]], [[Resolution|resolution]] 2.41Å' scene=''> | + | <StructureSection load='6e35' size='340' side='right'caption='[[6e35]], [[Resolution|resolution]] 2.41Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6e35]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E35 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6e35]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E35 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>, <scene name='pdbligand=ZCW:2-(1H-indol-3-yl)ethanol'>ZCW</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.411Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>, <scene name='pdbligand=ZCW:2-(1H-indol-3-yl)ethanol'>ZCW</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e35 OCA], [https://pdbe.org/6e35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e35 RCSB], [https://www.ebi.ac.uk/pdbsum/6e35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e35 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Forouhar | + | [[Category: Large Structures]] |
| - | [[Category: Hussain | + | [[Category: Forouhar F]] |
| - | [[Category: Karkashon | + | [[Category: Hussain M]] |
| - | [[Category: Lew | + | [[Category: Karkashon S]] |
| - | [[Category: Lewis-Ballester | + | [[Category: Lew S]] |
| - | [[Category: Lu | + | [[Category: Lewis-Ballester A]] |
| - | + | [[Category: Lu C]] | |
| - | [[Category: Seetharaman | + | [[Category: Seetharaman J]] |
| - | [[Category: Tong | + | [[Category: Tong L]] |
| - | [[Category: Yeh | + | [[Category: Yeh S-R]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160
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Categories: Homo sapiens | Large Structures | Forouhar F | Hussain M | Karkashon S | Lew S | Lewis-Ballester A | Lu C | Seetharaman J | Tong L | Yeh S-R
