This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6myk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:41, 11 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Pleurotus ostreatus OstreolysinA mutant E69A with Bis-Tris==
==Pleurotus ostreatus OstreolysinA mutant E69A with Bis-Tris==
-
<StructureSection load='6myk' size='340' side='right' caption='[[6myk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+
<StructureSection load='6myk' size='340' side='right'caption='[[6myk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6myk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Oyster_mushroom Oyster mushroom]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MYK FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6myk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pleurotus_ostreatus Pleurotus ostreatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MYK FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OlyA6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5322 Oyster mushroom])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6myk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6myk OCA], [http://pdbe.org/6myk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6myk RCSB], [http://www.ebi.ac.uk/pdbsum/6myk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6myk ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6myk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6myk OCA], [https://pdbe.org/6myk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6myk RCSB], [https://www.ebi.ac.uk/pdbsum/6myk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6myk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/OLYA6_PLEOS OLYA6_PLEOS]] Has hemolytic activity against bovine erythrocytes at nanomolar concentrations in vitro. Promotes active pleurotolysin B (PlyB)-dependent permeabilization of membranes rich in cholesterol and sphingomyelin. May play an important role in the initial phase of fungal fruiting.<ref>PMID:12020804</ref> <ref>PMID:23806422</ref>
+
[https://www.uniprot.org/uniprot/OLYA6_PLEOS OLYA6_PLEOS] Has hemolytic activity against bovine erythrocytes at nanomolar concentrations in vitro. Promotes active pleurotolysin B (PlyB)-dependent permeabilization of membranes rich in cholesterol and sphingomyelin. May play an important role in the initial phase of fungal fruiting.<ref>PMID:12020804</ref> <ref>PMID:23806422</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Oyster mushroom]]
+
[[Category: Large Structures]]
-
[[Category: Endapally, S]]
+
[[Category: Pleurotus ostreatus]]
-
[[Category: Radhakrishnan, A]]
+
[[Category: Endapally S]]
-
[[Category: Tomchick, D R]]
+
[[Category: Radhakrishnan A]]
-
[[Category: Beta-sandwich fold]]
+
[[Category: Tomchick DR]]
-
[[Category: Membrane binding protein]]
+
-
[[Category: Membrane protein]]
+

Current revision

Pleurotus ostreatus OstreolysinA mutant E69A with Bis-Tris

PDB ID 6myk

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6myk"
Personal tools