This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6ndu
From Proteopedia
(Difference between revisions)
m (Protected "6ndu" [edit=sysop:move=sysop]) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human PACRG-MEIG1 complex== | |
| - | + | <StructureSection load='6ndu' size='340' side='right'caption='[[6ndu]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ndu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NDU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ndu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ndu OCA], [https://pdbe.org/6ndu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ndu RCSB], [https://www.ebi.ac.uk/pdbsum/6ndu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ndu ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Khan | + | == Function == |
| - | [[Category: Trempe | + | [https://www.uniprot.org/uniprot/PACRG_HUMAN PACRG_HUMAN] Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.<ref>PMID:14532270</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Croteau N]] | ||
| + | [[Category: Khan N]] | ||
| + | [[Category: Pelletier D]] | ||
| + | [[Category: Trempe JF]] | ||
| + | [[Category: Veyron S]] | ||
Current revision
Structure of human PACRG-MEIG1 complex
| |||||||||||
