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6o9v

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Current revision (07:06, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6o9v' size='340' side='right'caption='[[6o9v]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
<StructureSection load='6o9v' size='340' side='right'caption='[[6o9v]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6o9v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O9V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6O9V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6o9v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O9V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DDQ:DECYLAMINE-N,N-DIMETHYL-N-OXIDE'>DDQ</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M1M:1,1-Methanediyl+Bismethanethiosulfonate'>M1M</scene>, <scene name='pdbligand=TMO:TRIMETHYLAMINE+OXIDE'>TMO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.094&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6o9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o9v OCA], [http://pdbe.org/6o9v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o9v RCSB], [http://www.ebi.ac.uk/pdbsum/6o9v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o9v ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DDQ:DECYLAMINE-N,N-DIMETHYL-N-OXIDE'>DDQ</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M1M:1,1-Methanediyl+Bismethanethiosulfonate'>M1M</scene>, <scene name='pdbligand=TMO:TRIMETHYLAMINE+OXIDE'>TMO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o9v OCA], [https://pdbe.org/6o9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o9v RCSB], [https://www.ebi.ac.uk/pdbsum/6o9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o9v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG]] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
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[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 31632]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Black, K A]]
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[[Category: Magnetospirillum magnetotacticum]]
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[[Category: Gulbis, J M]]
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[[Category: Black KA]]
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[[Category: Miller, D M]]
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[[Category: Gulbis JM]]
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[[Category: Membrane protein]]
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[[Category: Miller DM]]

Current revision

KirBac3.1 mutant at a resolution of 3.1 Angstroms

PDB ID 6o9v

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