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6pdm

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Current revision (07:27, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6pdm' size='340' side='right'caption='[[6pdm]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='6pdm' size='340' side='right'caption='[[6pdm]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6pdm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PDM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6pdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PDM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_protein_arginine_methyltransferase Type II protein arginine methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.320 2.1.1.320] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pdm OCA], [http://pdbe.org/6pdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pdm RCSB], [http://www.ebi.ac.uk/pdbsum/6pdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pdm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pdm OCA], [https://pdbe.org/6pdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pdm RCSB], [https://www.ebi.ac.uk/pdbsum/6pdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pdm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ANM9_HUMAN ANM9_HUMAN]] Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA (PubMed:25737013, PubMed:25979344).<ref>PMID:25737013</ref> <ref>PMID:25979344</ref>
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[https://www.uniprot.org/uniprot/ANM9_HUMAN ANM9_HUMAN] Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA (PubMed:25737013, PubMed:25979344).<ref>PMID:25737013</ref> <ref>PMID:25979344</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Type II protein arginine methyltransferase]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: Halabelian L]]
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[[Category: Halabelian, L]]
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[[Category: Hutchinson A]]
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[[Category: Hutchinson, A]]
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[[Category: Li Y]]
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[[Category: Li, Y]]
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[[Category: Seitova A]]
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[[Category: Structural genomic]]
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[[Category: Tempel W]]
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[[Category: Seitova, A]]
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[[Category: Zeng H]]
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[[Category: Tempel, W]]
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[[Category: Zeng, H]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)

PDB ID 6pdm

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