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6ulb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6ulb is ON HOLD Authors: Round, P.W., Das, S., Van Petegem, F. Description: Sex Hormone-binding globulin mutant E176K in complex with Danazol [[Cat...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Sex Hormone-binding globulin mutant E176K in complex with Danazol== | |
| - | + | <StructureSection load='6ulb' size='340' side='right'caption='[[6ulb]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ulb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ULB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ULB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=QA1:Danazol'>QA1</scene></td></tr> |
| - | [[Category: Das | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ulb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ulb OCA], [https://pdbe.org/6ulb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ulb RCSB], [https://www.ebi.ac.uk/pdbsum/6ulb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ulb ProSAT]</span></td></tr> |
| - | [[Category: Round | + | </table> |
| - | [[Category: Van Petegem | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SHBG_HUMAN SHBG_HUMAN] Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Das S]] | ||
| + | [[Category: Round PW]] | ||
| + | [[Category: Van Petegem F]] | ||
Current revision
Sex Hormone-binding globulin mutant E176K in complex with Danazol
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