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6v1c

From Proteopedia

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Current revision (08:02, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6v1c' size='340' side='right'caption='[[6v1c]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='6v1c' size='340' side='right'caption='[[6v1c]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6v1c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V1C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V1C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6v1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V1C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4A4:N/A4-O-[2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL]-BETA-D-GALACTOPYRANOSE'>4A4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TFF3, ITF, TFI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v1c OCA], [https://pdbe.org/6v1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v1c RCSB], [https://www.ebi.ac.uk/pdbsum/6v1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v1c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v1c OCA], [http://pdbe.org/6v1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v1c RCSB], [http://www.ebi.ac.uk/pdbsum/6v1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v1c ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TFF3_HUMAN TFF3_HUMAN]] Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).<ref>PMID:11694446</ref>
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[https://www.uniprot.org/uniprot/TFF3_HUMAN TFF3_HUMAN] Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).<ref>PMID:11694446</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Goddard-Borger, E D]]
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[[Category: Goddard-Borger ED]]
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[[Category: Jarva, M A]]
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[[Category: Jarva MA]]
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[[Category: John, A]]
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[[Category: John A]]
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[[Category: Lingford, J P]]
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[[Category: Lingford JP]]
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[[Category: Scott, N E]]
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[[Category: Scott NE]]
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[[Category: Lectin]]
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[[Category: Mucin binding protein]]
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[[Category: Sugar binding protein]]
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[[Category: Trefoil factor]]
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Current revision

Crystal structure of human trefoil factor 3 in complex with its cognate ligand

PDB ID 6v1c

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