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5lbu
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5lbu is ON HOLD Authors: Schneider, S., Gross, O. Description: Structure of the human quinone reductase 2 (NQO2) in complex with to CL097 [[Categor...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the human quinone reductase 2 (NQO2) in complex with to CL097== | |
| + | <StructureSection load='5lbu' size='340' side='right'caption='[[5lbu]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5lbu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LBU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C09:2-(ETHOXYMETHYL)-1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINE'>C09</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbu OCA], [https://pdbe.org/5lbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lbu RCSB], [https://www.ebi.ac.uk/pdbsum/5lbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Quinone reductase 3D structures|Quinone reductase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Gross | + | __TOC__ |
| - | [[Category: Schneider | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gross O]] | ||
| + | [[Category: Schneider S]] | ||
Current revision
Structure of the human quinone reductase 2 (NQO2) in complex with to CL097
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