This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5le1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:57, 11 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==VIM-2 metallo-beta-lactamase in complex with 2-(2-chloro-6-fluorobenzyl)-3-oxoisoindoline-4-carboxylic acid (compound 16)==
==VIM-2 metallo-beta-lactamase in complex with 2-(2-chloro-6-fluorobenzyl)-3-oxoisoindoline-4-carboxylic acid (compound 16)==
-
<StructureSection load='5le1' size='340' side='right' caption='[[5le1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
+
<StructureSection load='5le1' size='340' side='right'caption='[[5le1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5le1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LE1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LE1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5le1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LE1 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6UW:2-[(2-CHLORANYL-6-FLUORANYL-PHENYL)METHYL]-3-OXIDANYLIDENE-1~{H}-ISOINDOLE-4-CARBOXYLIC+ACID'>6UW</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5le1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5le1 OCA], [http://pdbe.org/5le1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5le1 RCSB], [http://www.ebi.ac.uk/pdbsum/5le1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5le1 ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6UW:2-[(2-CHLORANYL-6-FLUORANYL-PHENYL)METHYL]-3-OXIDANYLIDENE-1~{H}-ISOINDOLE-4-CARBOXYLIC+ACID'>6UW</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5le1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5le1 OCA], [https://pdbe.org/5le1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5le1 RCSB], [https://www.ebi.ac.uk/pdbsum/5le1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5le1 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9K2N0_PSEAI Q9K2N0_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 21:
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Brem, J]]
+
[[Category: Large Structures]]
-
[[Category: Li, G B]]
+
[[Category: Pseudomonas aeruginosa]]
-
[[Category: McDonough, M A]]
+
[[Category: Brem J]]
-
[[Category: Schofield, C J]]
+
[[Category: Li G-B]]
-
[[Category: Antibiotic resistance]]
+
[[Category: McDonough MA]]
-
[[Category: Complex]]
+
[[Category: Schofield CJ]]
-
[[Category: Hydrolase]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Metallo-beta-lactamase]]
+

Current revision

VIM-2 metallo-beta-lactamase in complex with 2-(2-chloro-6-fluorobenzyl)-3-oxoisoindoline-4-carboxylic acid (compound 16)

PDB ID 5le1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5le1"
Personal tools