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5ler

From Proteopedia

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Current revision (08:57, 11 October 2023) (edit) (undo)
 
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<SX load='5ler' size='340' side='right' viewer='molstar' caption='[[5ler]], [[Resolution|resolution]] 5.00&Aring;' scene=''>
<SX load='5ler' size='340' side='right' viewer='molstar' caption='[[5ler]], [[Resolution|resolution]] 5.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ler]] is a 75 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LER OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LER FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ler]] is a 75 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LER FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6V6:[(2~{S})-3-[[(2~{R})-2,3-BIS(OXIDANYL)PROPOXY]-OXIDANYL-PHOSPHORYL]OXY-2-HEXADEC-9-ENOYLOXY-PROPYL]+HEXADECANOATE'>6V6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ler FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ler OCA], [http://pdbe.org/5ler PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ler RCSB], [http://www.ebi.ac.uk/pdbsum/5ler PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ler ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6V6:[(2~{S})-3-[[(2~{R})-2,3-BIS(OXIDANYL)PROPOXY]-OXIDANYL-PHOSPHORYL]OXY-2-HEXADEC-9-ENOYLOXY-PROPYL]+HEXADECANOATE'>6V6</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ler FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ler OCA], [https://pdbe.org/5ler PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ler RCSB], [https://www.ebi.ac.uk/pdbsum/5ler PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ler ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PIL2_ECOLX PIL2_ECOLX]] Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established. Mature pilin is assembled with the help of TraQ and TraX (By similarity).
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[https://www.uniprot.org/uniprot/PIL1_ECOLI PIL1_ECOLI] Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established. Mature pilin is assembled with the help of TraQ and TraX (PubMed:1464628, PubMed:6090426). Functions as a receptor for CdiA-CT from E.cloacae and E.coli, although it is not clear if this is physiologically relevant (PubMed:24889811).<ref>PMID:1464628</ref> <ref>PMID:24889811</ref> <ref>PMID:6090426</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Costa, T R.D]]
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[[Category: Costa TRD]]
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[[Category: Egelman, E H]]
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[[Category: Egelman EH]]
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[[Category: Ilangovan, I]]
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[[Category: Ilangovan I]]
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[[Category: Redzej, A]]
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[[Category: Redzej A]]
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[[Category: Santini, J M]]
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[[Category: Santini JM]]
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[[Category: Smith, T K]]
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[[Category: Smith TK]]
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[[Category: Ukleja, M]]
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[[Category: Ukleja M]]
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[[Category: Waksman, G]]
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[[Category: Waksman G]]
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[[Category: Cell adhesion]]
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[[Category: F-pilus conjugation type iv secretion system phospholipid]]
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[[Category: Protein fibril]]
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Current revision

Structure of the bacterial sex F pilus (13.2 Angstrom rise)

5ler, resolution 5.00Å

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