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8et0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8et0 is ON HOLD until 2024-10-15 Authors: Xu, S., Banerjee, S., Uddin, M.J., Goodman, M.C., Marnett, L.J. Description: Crystal Complex of murine Cy...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9== | |
| - | + | <StructureSection load='8et0' size='340' side='right'caption='[[8et0]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8et0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ET0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ET0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IBP:IBUPROFEN'>IBP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8et0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8et0 OCA], [https://pdbe.org/8et0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8et0 RCSB], [https://www.ebi.ac.uk/pdbsum/8et0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8et0 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Banerjee | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/PGH2_MOUSE PGH2_MOUSE] Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.<ref>PMID:12925531</ref> <ref>PMID:20463020</ref> <ref>PMID:20810665</ref> <ref>PMID:21489986</ref> |
| - | [[Category: Marnett | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Vicugna pacos]] | ||
| + | [[Category: Banerjee S]] | ||
| + | [[Category: Goodman MC]] | ||
| + | [[Category: Marnett LJ]] | ||
| + | [[Category: Uddin MJ]] | ||
| + | [[Category: Xu S]] | ||
Current revision
Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9
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