This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8hpt
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of C5a-pep bound mouse C5aR1 in complex with Go== | |
| - | + | <StructureSection load='8hpt' size='340' side='right'caption='[[8hpt]], [[Resolution|resolution]] 3.39Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hpt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HPT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.39Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALC:2-AMINO-3-CYCLOHEXYL-PROPIONIC+ACID'>ALC</scene>, <scene name='pdbligand=DAR:D-ARGININE'>DAR</scene>, <scene name='pdbligand=MEA:N-METHYLPHENYLALANINE'>MEA</scene>, <scene name='pdbligand=ZAL:3-CYCLOHEXYL-D-ALANINE'>ZAL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hpt OCA], [https://pdbe.org/8hpt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hpt RCSB], [https://www.ebi.ac.uk/pdbsum/8hpt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hpt ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Chami | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/C5AR1_MOUSE C5AR1_MOUSE] Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB:P21730] |
| - | [[Category: Sarma | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Banerjee R]] | ||
| + | [[Category: Chami M]] | ||
| + | [[Category: Maharana J]] | ||
| + | [[Category: Saha S]] | ||
| + | [[Category: Sarma P]] | ||
| + | [[Category: Shukla AK]] | ||
| + | [[Category: Yadav MK]] | ||
Current revision
Structure of C5a-pep bound mouse C5aR1 in complex with Go
| |||||||||||
Categories: Homo sapiens | Large Structures | Mus musculus | Synthetic construct | Banerjee R | Chami M | Maharana J | Saha S | Sarma P | Shukla AK | Yadav MK
