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8hqc
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8hqc is ON HOLD Authors: Saha, S., Maharana, J., Yadav, M.K., Sarma, P., Chami, M., Banerjee, R., Shukla, A.K. Description: Structure of a GPCR-G p...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a GPCR-G protein in complex with a natural peptide agonist== | |
| - | + | <StructureSection load='8hqc' size='340' side='right'caption='[[8hqc]], [[Resolution|resolution]] 3.89Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hqc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HQC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.89Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hqc OCA], [https://pdbe.org/8hqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hqc RCSB], [https://www.ebi.ac.uk/pdbsum/8hqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hqc ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/C5AR1_MOUSE C5AR1_MOUSE] Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB:P21730] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Maharana | + | </StructureSection> |
| - | [[Category: Saha | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Banerjee R]] | ||
| + | [[Category: Chami M]] | ||
| + | [[Category: Maharana J]] | ||
| + | [[Category: Saha S]] | ||
| + | [[Category: Sarma P]] | ||
| + | [[Category: Shukla AK]] | ||
| + | [[Category: Yadav MK]] | ||
Current revision
Structure of a GPCR-G protein in complex with a natural peptide agonist
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Categories: Homo sapiens | Large Structures | Mus musculus | Banerjee R | Chami M | Maharana J | Saha S | Sarma P | Shukla AK | Yadav MK
