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6w4l

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Current revision (14:16, 18 October 2023) (edit) (undo)
 
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<StructureSection load='6w4l' size='340' side='right'caption='[[6w4l]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
<StructureSection load='6w4l' size='340' side='right'caption='[[6w4l]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6w4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W4L OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6W4L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6w4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6W4L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6w4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w4l OCA], [http://pdbe.org/6w4l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6w4l RCSB], [http://www.ebi.ac.uk/pdbsum/6w4l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6w4l ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6w4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w4l OCA], [https://pdbe.org/6w4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6w4l RCSB], [https://www.ebi.ac.uk/pdbsum/6w4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6w4l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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[https://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.[https://www.uniprot.org/uniprot/H2A1_XENLA H2A1_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6w4l" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6w4l" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histone 3D structures|Histone 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: African clawed frog]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Xenopus laevis]]
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[[Category: Bonanno, J B]]
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[[Category: Almo SC]]
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[[Category: Shechter, D]]
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[[Category: Bonanno JB]]
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[[Category: Warren, C]]
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[[Category: Shechter D]]
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[[Category: Chromatin]]
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[[Category: Warren C]]
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[[Category: Gene regulation]]
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[[Category: Histone]]
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Current revision

The crystal structure of a single chain H2B-H2A histone chimera from Xenopus laevis

PDB ID 6w4l

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