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6wmv
From Proteopedia
(Difference between revisions)
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<StructureSection load='6wmv' size='340' side='right'caption='[[6wmv]], [[Resolution|resolution]] 2.14Å' scene=''> | <StructureSection load='6wmv' size='340' side='right'caption='[[6wmv]], [[Resolution|resolution]] 2.14Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6wmv]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6wmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus] and [https://en.wikipedia.org/wiki/Mycobacterium_kansasii_ATCC_12478 Mycobacterium kansasii ATCC 12478]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WMV FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=8K6:OCTADECANE'>8K6</scene>, <scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LIP:L-MYO-INOSITOL-1-PHOSPHATE'>LIP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=TCE:3,3,3-PHOSPHANETRIYLTRIPROPANOIC+ACID'>TCE</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.142Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=8K6:OCTADECANE'>8K6</scene>, <scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LIP:L-MYO-INOSITOL-1-PHOSPHATE'>LIP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=TCE:3,3,3-PHOSPHANETRIYLTRIPROPANOIC+ACID'>TCE</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wmv OCA], [https://pdbe.org/6wmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wmv RCSB], [https://www.ebi.ac.uk/pdbsum/6wmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wmv ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/O27985_ARCFU O27985_ARCFU] [https://www.uniprot.org/uniprot/U5WZP7_MYCKA U5WZP7_MYCKA] Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.[HAMAP-Rule:MF_02241] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Archaeoglobus fulgidus]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Ashraf | + | [[Category: Mycobacterium kansasii ATCC 12478]] |
| - | [[Category: Banerjee | + | [[Category: Ashraf KU]] |
| - | [[Category: | + | [[Category: Banerjee S]] |
| - | [[Category: | + | [[Category: Belcher Dufrisne M]] |
| - | [[Category: Jorge | + | [[Category: Clarke OB]] |
| - | [[Category: Mancia | + | [[Category: Jorge CD]] |
| - | [[Category: Petrou | + | [[Category: Mancia F]] |
| - | [[Category: Santos | + | [[Category: Petrou VI]] |
| - | [[Category: Timoteo | + | [[Category: Santos H]] |
| - | + | [[Category: Timoteo CG]] | |
| - | + | ||
Current revision
Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii with evidence of substrate binding
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