7m0c
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Post-catalytic nicked complex of DNA Polymerase Lambda with bound mismatched DSB substrate== |
| - | <StructureSection load='7m0c' size='340' side='right'caption='[[7m0c]]' scene=''> | + | <StructureSection load='7m0c' size='340' side='right'caption='[[7m0c]], [[Resolution|resolution]] 2.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7m0c]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M0C FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m0c OCA], [https://pdbe.org/7m0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m0c RCSB], [https://www.ebi.ac.uk/pdbsum/7m0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m0c ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m0c OCA], [https://pdbe.org/7m0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m0c RCSB], [https://www.ebi.ac.uk/pdbsum/7m0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m0c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Synthetic construct]] |
| + | [[Category: Bebenek K]] | ||
| + | [[Category: Kaminski AM]] | ||
| + | [[Category: Kunkel TA]] | ||
| + | [[Category: Pedersen LC]] | ||
Current revision
Post-catalytic nicked complex of DNA Polymerase Lambda with bound mismatched DSB substrate
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