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7tps
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1== | |
| - | + | <StructureSection load='7tps' size='340' side='right'caption='[[7tps]], [[Resolution|resolution]] 3.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7tps]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TPS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tps OCA], [https://pdbe.org/7tps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tps RCSB], [https://www.ebi.ac.uk/pdbsum/7tps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tps ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD80_HUMAN CD80_HUMAN] Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Akutsu M]] | ||
| + | [[Category: Demonte DW]] | ||
| + | [[Category: Kimbung YR]] | ||
| + | [[Category: Logan DT]] | ||
| + | [[Category: Maurer MF]] | ||
| + | [[Category: Walse B]] | ||
Current revision
Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1
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Categories: Homo sapiens | Large Structures | Akutsu M | Demonte DW | Kimbung YR | Logan DT | Maurer MF | Walse B
