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8du3

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<StructureSection load='8du3' size='340' side='right'caption='[[8du3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='8du3' size='340' side='right'caption='[[8du3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[8du3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DU3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[8du3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DU3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=TKO:(4M)-6-bromo-4-(furan-2-yl)quinazolin-2-amine'>TKO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=TKO:(4M)-6-bromo-4-(furan-2-yl)quinazolin-2-amine'>TKO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8du3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8du3 OCA], [https://pdbe.org/8du3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8du3 RCSB], [https://www.ebi.ac.uk/pdbsum/8du3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8du3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8du3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8du3 OCA], [https://pdbe.org/8du3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8du3 RCSB], [https://www.ebi.ac.uk/pdbsum/8du3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8du3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cherezov, V]]
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[[Category: Cherezov V]]
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[[Category: Han, G W]]
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[[Category: Han GW]]
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[[Category: Shiriaeva, A]]
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[[Category: Shiriaeva A]]
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[[Category: Stauch, B]]
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[[Category: Stauch B]]
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[[Category: Alzheimer]]
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[[Category: Antagonist]]
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[[Category: Gpcr]]
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[[Category: Lcp]]
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[[Category: Membrane protein]]
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[[Category: Parkinson]]
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Current revision

Crystal structure of A2AAR-StaR2-bRIL in complex with compound 21a

PDB ID 8du3

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