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1iup

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==meta-Cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) S103A mutant complexed with isobutyrates==
==meta-Cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) S103A mutant complexed with isobutyrates==
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<StructureSection load='1iup' size='340' side='right' caption='[[1iup]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='1iup' size='340' side='right'caption='[[1iup]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1iup]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_liquefaciens"_flugge_1886 "bacillus fluorescens liquefaciens" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IUP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1iup]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IUP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALQ:2-METHYL-PROPIONIC+ACID'>ALQ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1iun|1iun]], [[1iuo|1iuo]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALQ:2-METHYL-PROPIONIC+ACID'>ALQ</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cumD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=294 "Bacillus fluorescens liquefaciens" Flugge 1886])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iup OCA], [https://pdbe.org/1iup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iup RCSB], [https://www.ebi.ac.uk/pdbsum/1iup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iup ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-hydroxymuconate-6-semialdehyde_hydrolase 2-hydroxymuconate-6-semialdehyde hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.9 3.7.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iup OCA], [http://pdbe.org/1iup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iup RCSB], [http://www.ebi.ac.uk/pdbsum/1iup PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P96965_PSEFL P96965_PSEFL]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/1iup_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/1iup_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iup ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus fluorescens liquefaciens flugge 1886]]
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[[Category: Large Structures]]
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[[Category: 2-hydroxymuconate-6-semialdehyde hydrolase]]
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[[Category: Pseudomonas fluorescens]]
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[[Category: Fushinobu, S]]
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[[Category: Fushinobu S]]
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[[Category: Hidaka, M]]
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[[Category: Hidaka M]]
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[[Category: Jun, S Y]]
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[[Category: Jun S-Y]]
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[[Category: Nojiri, H]]
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[[Category: Nojiri H]]
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[[Category: Omori, T]]
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[[Category: Omori T]]
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[[Category: Saku, T]]
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[[Category: Saku T]]
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[[Category: Shoun, H]]
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[[Category: Shoun H]]
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[[Category: Wakagi, T]]
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[[Category: Wakagi T]]
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[[Category: Yamane, H]]
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[[Category: Yamane H]]
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[[Category: Alpha/beta-hydrolase]]
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[[Category: Aromatic compound]]
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[[Category: Beta-ketolase]]
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[[Category: Cumene]]
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[[Category: Cumene degradation]]
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[[Category: Hydrolase]]
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[[Category: Isopropylbenzene]]
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[[Category: Meta-cleavage compound hydrolase]]
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[[Category: Pcb]]
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[[Category: Polychlorinated biphenyl degradation]]
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[[Category: Pseudomonas fluorescens ip01]]
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[[Category: Substrate specificity]]
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Current revision

meta-Cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) S103A mutant complexed with isobutyrates

PDB ID 1iup

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