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1roa

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==Structure of human cystatin D==
==Structure of human cystatin D==
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<StructureSection load='1roa' size='340' side='right' caption='[[1roa]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='1roa' size='340' side='right'caption='[[1roa]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1roa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ROA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1roa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ROA FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rn7|1rn7]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1roa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1roa OCA], [http://pdbe.org/1roa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1roa RCSB], [http://www.ebi.ac.uk/pdbsum/1roa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1roa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1roa OCA], [https://pdbe.org/1roa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1roa RCSB], [https://www.ebi.ac.uk/pdbsum/1roa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1roa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CYTD_HUMAN CYTD_HUMAN]] Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B.<ref>PMID:8083219</ref>
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[https://www.uniprot.org/uniprot/CYTD_HUMAN CYTD_HUMAN] Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B.<ref>PMID:8083219</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1roa_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1roa_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Abrahamson, M]]
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[[Category: Large Structures]]
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[[Category: Alvarez-Fernandez, M]]
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[[Category: Abrahamson M]]
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[[Category: Liang, Y H]]
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[[Category: Alvarez-Fernandez M]]
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[[Category: Su, X D]]
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[[Category: Liang YH]]
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[[Category: Cystatin d]]
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[[Category: Su XD]]
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[[Category: Inhibitor of cysteine pepidase]]
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[[Category: Protein binding]]
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Current revision

Structure of human cystatin D

PDB ID 1roa

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