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1v4n

From Proteopedia

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(New page: 200px<br /><applet load="1v4n" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v4n, resolution 2.45&Aring;" /> '''Structure of 5'-deox...)
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[[Image:1v4n.gif|left|200px]]<br /><applet load="1v4n" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1v4n, resolution 2.45&Aring;" />
 
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'''Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii'''<br />
 
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==About this Structure==
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==Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii==
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1V4N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Active as [http://en.wikipedia.org/wiki/S-methyl-5-thioadenosine_phosphorylase S-methyl-5-thioadenosine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.28 2.4.2.28] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V4N OCA].
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<StructureSection load='1v4n' size='340' side='right'caption='[[1v4n]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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[[Category: S-methyl-5-thioadenosine phosphorylase]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1v4n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V4N FirstGlance]. <br>
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[[Category: Sulfolobus tokodaii]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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[[Category: Kawarabayasi, Y.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4n OCA], [https://pdbe.org/1v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v4n RCSB], [https://www.ebi.ac.uk/pdbsum/1v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v4n ProSAT]</span></td></tr>
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[[Category: Kitago, Y.]]
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</table>
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[[Category: Sakai, N.]]
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== Function ==
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[[Category: Tanaka, I.]]
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[https://www.uniprot.org/uniprot/F9VN03_SULTO F9VN03_SULTO] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963]
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[[Category: Tsujimura, M.]]
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== Evolutionary Conservation ==
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[[Category: Watanabe, N.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Yao, M.]]
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Check<jmol>
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[[Category: Yasutake, Y.]]
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<jmolCheckbox>
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[[Category: structural genomics]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/1v4n_consurf.spt"</scriptWhenChecked>
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[[Category: transferase]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 04:35:54 2007''
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v4n ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Sulfurisphaera tokodaii]]
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[[Category: Kawarabayasi Y]]
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[[Category: Kitago Y]]
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[[Category: Sakai N]]
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[[Category: Tanaka I]]
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[[Category: Tsujimura M]]
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[[Category: Watanabe N]]
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[[Category: Yao M]]
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[[Category: Yasutake Y]]

Current revision

Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii

PDB ID 1v4n

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