This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1v53
From Proteopedia
(Difference between revisions)
| (14 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1v53.gif|left|200px]]<br /><applet load="1v53" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1v53, resolution 2.85Å" /> | ||
| - | '''The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans'''<br /> | ||
| - | == | + | ==The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans== |
| - | + | <StructureSection load='1v53' size='340' side='right'caption='[[1v53]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1v53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Weizmannia_coagulans Weizmannia coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V53 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v53 OCA], [https://pdbe.org/1v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v53 RCSB], [https://www.ebi.ac.uk/pdbsum/1v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v53 ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/LEU3_WEICA LEU3_WEICA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v53_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v53 ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | + | ==See Also== | |
| + | *[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Weizmannia coagulans]] | ||
| + | [[Category: Fujita K]] | ||
| + | [[Category: Minami H]] | ||
| + | [[Category: Mizui R]] | ||
| + | [[Category: Nakamura S]] | ||
| + | [[Category: Sekiguchi T]] | ||
| + | [[Category: Suzuki K]] | ||
| + | [[Category: Takenaka A]] | ||
| + | [[Category: Tsunoda M]] | ||
| + | [[Category: Tsuzaki S]] | ||
Current revision
The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans
| |||||||||||
Categories: Large Structures | Weizmannia coagulans | Fujita K | Minami H | Mizui R | Nakamura S | Sekiguchi T | Suzuki K | Takenaka A | Tsunoda M | Tsuzaki S
