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1v53

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Current revision (07:47, 25 October 2023) (edit) (undo)
 
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<StructureSection load='1v53' size='340' side='right'caption='[[1v53]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='1v53' size='340' side='right'caption='[[1v53]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1v53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_7050 Atcc 7050]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V53 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1v53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Weizmannia_coagulans Weizmannia coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V53 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v53 OCA], [https://pdbe.org/1v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v53 RCSB], [https://www.ebi.ac.uk/pdbsum/1v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v53 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v53 OCA], [https://pdbe.org/1v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v53 RCSB], [https://www.ebi.ac.uk/pdbsum/1v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v53 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LEU3_BACCO LEU3_BACCO]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
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[https://www.uniprot.org/uniprot/LEU3_WEICA LEU3_WEICA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-isopropylmalate dehydrogenase]]
 
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[[Category: Atcc 7050]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fujita, K]]
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[[Category: Weizmannia coagulans]]
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[[Category: Minami, H]]
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[[Category: Fujita K]]
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[[Category: Mizui, R]]
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[[Category: Minami H]]
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[[Category: Nakamura, S]]
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[[Category: Mizui R]]
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[[Category: Sekiguchi, T]]
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[[Category: Nakamura S]]
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[[Category: Suzuki, K]]
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[[Category: Sekiguchi T]]
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[[Category: Takenaka, A]]
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[[Category: Suzuki K]]
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[[Category: Tsunoda, M]]
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[[Category: Takenaka A]]
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[[Category: Tsuzaki, S]]
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[[Category: Tsunoda M]]
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[[Category: Bacillus coagulan]]
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[[Category: Tsuzaki S]]
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[[Category: Homo dimer]]
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[[Category: Ipmdh]]
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[[Category: Oxidoreductase]]
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[[Category: X-ray analysis]]
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Current revision

The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans

PDB ID 1v53

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