1v5b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1v5b" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v5b, resolution 2.95&Aring;" /> '''The Structure Of The...)
Current revision (07:47, 25 October 2023) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1v5b.gif|left|200px]]<br /><applet load="1v5b" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1v5b, resolution 2.95&Aring;" />
 
-
'''The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans'''<br />
 
-
==About this Structure==
+
==The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans==
-
1V5B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_coagulans Bacillus coagulans] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA].
+
<StructureSection load='1v5b' size='340' side='right'caption='[[1v5b]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
-
[[Category: 3-isopropylmalate dehydrogenase]]
+
== Structural highlights ==
-
[[Category: Bacillus coagulans]]
+
<table><tr><td colspan='2'>[[1v5b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Weizmannia_coagulans Weizmannia coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5B FirstGlance]. <br>
-
[[Category: Single protein]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
-
[[Category: Fujita, K.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Minami, H.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5b OCA], [https://pdbe.org/1v5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5b RCSB], [https://www.ebi.ac.uk/pdbsum/1v5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5b ProSAT]</span></td></tr>
-
[[Category: Mizui, R.]]
+
</table>
-
[[Category: Nakamura, S.]]
+
== Function ==
-
[[Category: Sekiguchi, T.]]
+
[https://www.uniprot.org/uniprot/LEU3_WEICA LEU3_WEICA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
-
[[Category: Suzuki, K.]]
+
== Evolutionary Conservation ==
-
[[Category: Takenaka, A.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Tsunoda, M.]]
+
Check<jmol>
-
[[Category: Tsuzaki, S.]]
+
<jmolCheckbox>
-
[[Category: SO4]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5b_consurf.spt"</scriptWhenChecked>
-
[[Category: 3-isopropylmalate dehydrogenase]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: bacillus coagulans]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: crystal structure]]
+
</jmolCheckbox>
-
[[Category: homo dimer]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5b ConSurf].
-
[[Category: ipmdh]]
+
<div style="clear:both"></div>
-
[[Category: mutant]]
+
-
[[Category: s225a/e251l]]
+
-
[[Category: x-ray analysis]]
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:26:49 2007''
+
==See Also==
 +
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Weizmannia coagulans]]
 +
[[Category: Fujita K]]
 +
[[Category: Minami H]]
 +
[[Category: Mizui R]]
 +
[[Category: Nakamura S]]
 +
[[Category: Sekiguchi T]]
 +
[[Category: Suzuki K]]
 +
[[Category: Takenaka A]]
 +
[[Category: Tsunoda M]]
 +
[[Category: Tsuzaki S]]

Current revision

The Structure Of The Mutant, S225A and E251L, Of 3-Isopropylmalate Dehydrogenase From Bacillus Coagulans

PDB ID 1v5b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1v5b"
Personal tools