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1vef

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==Acetylornithine aminotransferase from Thermus thermophilus HB8==
==Acetylornithine aminotransferase from Thermus thermophilus HB8==
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<StructureSection load='1vef' size='340' side='right' caption='[[1vef]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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<StructureSection load='1vef' size='340' side='right'caption='[[1vef]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vef]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VEF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vef]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VEF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylornithine_transaminase Acetylornithine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.11 2.6.1.11] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vef OCA], [http://pdbe.org/1vef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vef RCSB], [http://www.ebi.ac.uk/pdbsum/1vef PDBsum], [http://www.topsan.org/Proteins/RSGI/1vef TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vef OCA], [https://pdbe.org/1vef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vef RCSB], [https://www.ebi.ac.uk/pdbsum/1vef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vef ProSAT], [https://www.topsan.org/Proteins/RSGI/1vef TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARGD_THET2 ARGD_THET2]] Involved in both the arginine and lysine biosynthetic pathways (By similarity).
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[https://www.uniprot.org/uniprot/LYSJ_THET8 LYSJ_THET8] Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.[HAMAP-Rule:MF_02084]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/1vef_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/1vef_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
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[[Category: Large Structures]]
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[[Category: Acetylornithine transaminase]]
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[[Category: Thermus thermophilus]]
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[[Category: Goto, M]]
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[[Category: Goto M]]
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[[Category: Hirotsu, K]]
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[[Category: Hirotsu K]]
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[[Category: Matsumura, M]]
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[[Category: Matsumura M]]
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[[Category: Miyahara, I]]
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[[Category: Miyahara I]]
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[[Category: Omi, R]]
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[[Category: Omi R]]
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[[Category: Structural genomic]]
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[[Category: Aminotransferase]]
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[[Category: Plp]]
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[[Category: Rsgi]]
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[[Category: Transferase]]
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Current revision

Acetylornithine aminotransferase from Thermus thermophilus HB8

PDB ID 1vef

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