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1ysr
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1ysr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ysr, resolution 1.78Å" /> '''Crystal Structure of...) |
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| - | [[Image:1ysr.gif|left|200px]]<br /><applet load="1ysr" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1ysr, resolution 1.78Å" /> | ||
| - | '''Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis'''<br /> | ||
| - | == | + | ==Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis== |
| - | + | <StructureSection load='1ysr' size='340' side='right'caption='[[1ysr]], [[Resolution|resolution]] 1.78Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1ysr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YSR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ysr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ysr OCA], [https://pdbe.org/1ysr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ysr RCSB], [https://www.ebi.ac.uk/pdbsum/1ysr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ysr ProSAT], [https://www.topsan.org/Proteins/XMTB/1ysr TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PRRB_MYCTU PRRB_MYCTU] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium. Probably phosphorylates PrrA. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/1ysr_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ysr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | + | [[Category: Nowak E]] | |
| - | [[Category: Nowak | + | [[Category: Panjikar S]] |
| - | [[Category: Panjikar | + | [[Category: Tucker P]] |
| - | [[Category: Tucker | + | |
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Current revision
Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis
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