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1yup
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1yup" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yup, resolution 2.10Å" /> '''Reindeer beta-lactog...) |
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| - | [[Image:1yup.gif|left|200px]]<br /><applet load="1yup" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1yup, resolution 2.10Å" /> | ||
| - | '''Reindeer beta-lactoglobulin'''<br /> | ||
| - | == | + | ==Reindeer beta-lactoglobulin== |
| - | Reindeer beta-lactoglobulin (betaLG) belongs to the lipocalin superfamily. | + | <StructureSection load='1yup' size='340' side='right'caption='[[1yup]], [[Resolution|resolution]] 2.10Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1yup]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rangifer_tarandus Rangifer tarandus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YUP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yup OCA], [https://pdbe.org/1yup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yup RCSB], [https://www.ebi.ac.uk/pdbsum/1yup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yup ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q00P86_RANTA Q00P86_RANTA] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yu/1yup_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yup ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Reindeer beta-lactoglobulin (betaLG) belongs to the lipocalin superfamily. Its DNA and protein sequences have been determined and showed that it had nine residue changes from bovine betaLG. Reindeer betaLG, the structure of which was finally determined at 2.1 A resolution in space group P1, crystallized in a unit cell that is both P2-like and P2(1)-like owing to the presence of an almost perfect (but noncrystallographic) body-centring vector. The non-body-centred data could only be observed using a very bright synchrotron beam and a novel refinement strategy was adopted to enable us to use the weak h + k + l = 2n + 1 reflections. | ||
| - | + | Reindeer beta-lactoglobulin crystal structure with pseudo-body-centred noncrystallographic symmetry.,Oksanen E, Jaakola VP, Tolonen T, Valkonen K, Akerstrom B, Kalkkinen N, Virtanen V, Goldman A Acta Crystallogr D Biol Crystallogr. 2006 Nov;62(Pt 11):1369-74. Epub 2006, Oct 18. PMID:17057340<ref>PMID:17057340</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 1yup" style="background-color:#fffaf0;"></div> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Beta-lactoglobulin 3D structures|Beta-lactoglobulin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rangifer tarandus]] | ||
| + | [[Category: Goldman A]] | ||
| + | [[Category: Oksanen E]] | ||
Current revision
Reindeer beta-lactoglobulin
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