This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1yxm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:13, 25 October 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1yxm.gif|left|200px]]<br /><applet load="1yxm" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1yxm, resolution 1.90&Aring;" />
 
-
'''Crystal structure of peroxisomal trans 2-enoyl CoA reductase'''<br />
 
-
==About this Structure==
+
==Crystal structure of peroxisomal trans 2-enoyl CoA reductase==
-
1YXM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=ADE:'>ADE</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acyl-CoA_dehydrogenase_(NADP(+)) Acyl-CoA dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.8 1.3.1.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YXM OCA].
+
<StructureSection load='1yxm' size='340' side='right'caption='[[1yxm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
[[Category: Acyl-CoA dehydrogenase (NADP(+))]]
+
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1yxm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YXM FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yxm OCA], [https://pdbe.org/1yxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yxm RCSB], [https://www.ebi.ac.uk/pdbsum/1yxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yxm ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PECR_HUMAN PECR_HUMAN] Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/1yxm_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yxm ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Delft, F Von.]]
+
[[Category: Edwards AM]]
-
[[Category: Edwards, A M.]]
+
[[Category: Jansson A]]
-
[[Category: Jansson, A.]]
+
[[Category: Ng S]]
-
[[Category: Ng, S.]]
+
[[Category: Oppermann U]]
-
[[Category: Oppermann, U.]]
+
[[Category: Sharma S]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sharma, S.]]
+
[[Category: Von Delft F]]
-
[[Category: Sundstrom, M.]]
+
-
[[Category: ADE]]
+
-
[[Category: PO4]]
+
-
[[Category: SO4]]
+
-
[[Category: enoyl coa]]
+
-
[[Category: fatty acid synthesis]]
+
-
[[Category: perioxisomes]]
+
-
[[Category: sgc]]
+
-
[[Category: short-chain dehydrogenases/reductases]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:10:14 2008''
+

Current revision

Crystal structure of peroxisomal trans 2-enoyl CoA reductase

PDB ID 1yxm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1yxm"
Personal tools