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2dfd

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Current revision (08:26, 25 October 2023) (edit) (undo)
 
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<StructureSection load='2dfd' size='340' side='right'caption='[[2dfd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2dfd' size='340' side='right'caption='[[2dfd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dfd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dfd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mld|1mld]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDH2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfd OCA], [https://pdbe.org/2dfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfd RCSB], [https://www.ebi.ac.uk/pdbsum/2dfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfd OCA], [https://pdbe.org/2dfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfd RCSB], [https://www.ebi.ac.uk/pdbsum/2dfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfd ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MDHM_HUMAN MDHM_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Malate dehydrogenase]]
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[[Category: Arrowsmith C]]
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[[Category: Arrowsmith, C]]
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[[Category: Edwards A]]
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[[Category: Delft, F von]]
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[[Category: Oppermann U]]
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[[Category: Edwards, A]]
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[[Category: Rojkova A]]
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[[Category: Oppermann, U]]
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[[Category: Shafqat N]]
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[[Category: Rojkova, A]]
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[[Category: Sundstrom M]]
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[[Category: Structural genomic]]
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[[Category: Ugochukwu E]]
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[[Category: Shafqat, N]]
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[[Category: Weigelt J]]
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[[Category: Sundstrom, M]]
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[[Category: Von Delft F]]
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[[Category: Ugochukwu, E]]
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[[Category: Weigelt, J]]
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[[Category: Citric acid cycle]]
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[[Category: Dehydrogenase]]
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[[Category: Oxidoreductase]]
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[[Category: Sgc]]
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Current revision

Crystal Structure of Human Malate Dehydrogenase Type 2

PDB ID 2dfd

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