This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2dp4
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2dp4" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dp4, resolution 2.90Å" /> '''Crystal structure o...) |
|||
| (16 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2dp4.gif|left|200px]]<br /> | ||
| - | <applet load="2dp4" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2dp4, resolution 2.90Å" /> | ||
| - | '''Crystal structure of the complex formed between proteinase K and a human lactoferrin fragment at 2.9 A resolution'''<br /> | ||
| - | == | + | ==Crystal structure of the complex formed between proteinase K and a human lactoferrin fragment at 2.9 A resolution== |
| - | + | <StructureSection load='2dp4' size='340' side='right'caption='[[2dp4]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2dp4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DP4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dp4 OCA], [https://pdbe.org/2dp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dp4 RCSB], [https://www.ebi.ac.uk/pdbsum/2dp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dp4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dp4_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dp4 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Proteinase 3D structures|Proteinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Parengyodontium album]] |
| - | [[Category: Bhushan | + | [[Category: Bhushan A]] |
| - | [[Category: Sharma | + | [[Category: Sharma S]] |
| - | [[Category: Singh | + | [[Category: Singh AK]] |
| - | [[Category: Singh | + | [[Category: Singh N]] |
| - | [[Category: Singh | + | [[Category: Singh TP]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the complex formed between proteinase K and a human lactoferrin fragment at 2.9 A resolution
| |||||||||||
