This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2dtt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:29, 25 October 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2dtt.jpg|left|200px]]
 
-
{{Structure
+
==Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin==
-
|PDB= 2dtt |SIZE=350|CAPTION= <scene name='initialview01'>2dtt</scene>, resolution 2.20&Aring;
+
<StructureSection load='2dtt' size='340' side='right'caption='[[2dtt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>
+
<table><tr><td colspan='2'>[[2dtt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTT FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
|GENE= PH0634 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dtt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtt OCA], [https://pdbe.org/2dtt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dtt RCSB], [https://www.ebi.ac.uk/pdbsum/2dtt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dtt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dtt TOPSAN]</span></td></tr>
-
 
+
</table>
-
'''Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/O58368_PYRHO O58368_PYRHO]
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2DTT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTT OCA].
+
Check<jmol>
-
[[Category: Pyrococcus horikoshii]]
+
<jmolCheckbox>
-
[[Category: Single protein]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dtt_consurf.spt"</scriptWhenChecked>
-
[[Category: Bagautdinov, B.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Kunishima, N.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
</jmolCheckbox>
-
[[Category: H4B]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dtt ConSurf].
-
[[Category: 6-pyruvoyl tetrahydrobiopterin synthase (ptps)]]
+
<div style="clear:both"></div>
-
[[Category: biopterin]]
+
__TOC__
-
[[Category: national project on protein structural and functional analyse]]
+
</StructureSection>
-
[[Category: nppsfa]]
+
[[Category: Large Structures]]
-
[[Category: riken structural genomics/proteomics initiative]]
+
[[Category: Pyrococcus horikoshii OT3]]
-
[[Category: rsgi]]
+
[[Category: Bagautdinov B]]
-
[[Category: structural genomic]]
+
[[Category: Kunishima N]]
-
[[Category: x-ray diffraction]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:31:26 2008''
+

Current revision

Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin

PDB ID 2dtt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools