This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2dzx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2dzx" [edit=sysop:move=sysop])
Current revision (08:32, 25 October 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2dzx.png|left|200px]]
 
-
{{STRUCTURE_2dzx| PDB=2dzx | SCENE= }}
+
==Structure of mutant tryptophan synthase alpha-subunit (E131-132A) from a hyperthermophile, Pyrococcus furiosus==
 +
<StructureSection load='2dzx' size='340' side='right'caption='[[2dzx]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2dzx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZX FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzx OCA], [https://pdbe.org/2dzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzx RCSB], [https://www.ebi.ac.uk/pdbsum/2dzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzx TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRPA_PYRFU TRPA_PYRFU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/2dzx_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dzx ConSurf].
 +
<div style="clear:both"></div>
-
===Structure of mutant tryptophan synthase alpha-subunit (E131-132A) from a hyperthermophile, Pyrococcus furiosus===
+
==See Also==
-
 
+
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
-
{{ABSTRACT_PUBMED_11118452}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
[[2dzx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZX OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:011118452</ref><references group="xtra"/>
+
-
[[Category: Pyrococcus furiosus]]
+
-
[[Category: Tryptophan synthase]]
+
-
[[Category: Ogasahara, K.]]
+
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
-
[[Category: Yamagata, Y.]]
+
-
[[Category: Yutani, K.]]
+
-
[[Category: Calorimetry]]
+
-
[[Category: Hyperthermophile]]
+
-
[[Category: Lyase]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
-
[[Category: Riken structural genomics/proteomics initiative]]
+
[[Category: Ogasahara K]]
-
[[Category: Rsgi]]
+
[[Category: Yamagata Y]]
-
[[Category: Stability]]
+
[[Category: Yutani K]]
-
[[Category: Structural genomic]]
+
-
[[Category: Tryptophan synthase alpha-subunit]]
+
-
[[Category: X-ray analysis]]
+

Current revision

Structure of mutant tryptophan synthase alpha-subunit (E131-132A) from a hyperthermophile, Pyrococcus furiosus

PDB ID 2dzx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools