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2egy

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{{Seed}}
 
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[[Image:2egy.png|left|200px]]
 
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==Crystal structure of LysN, alpha-aminoadipate aminotransferase (substrate free form), from Thermus thermophilus HB27==
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The line below this paragraph, containing "STRUCTURE_2egy", creates the "Structure Box" on the page.
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<StructureSection load='2egy' size='340' side='right'caption='[[2egy]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2egy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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{{STRUCTURE_2egy| PDB=2egy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egy OCA], [https://pdbe.org/2egy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egy RCSB], [https://www.ebi.ac.uk/pdbsum/2egy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSN_THET2 LYSN_THET2] Catalyzes the transfer of an amino group between 2-oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also contributes in the biosynthesis of other amino acids such as leucine.<ref>PMID:15256574</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2egy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2egy ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of LysN, alpha-aminoadipate aminotransferase (substrate free form), from Thermus thermophilus HB27===
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==See Also==
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2EGY is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGY OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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<ref group="xtra">PMID:15256574</ref><references group="xtra"/>
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[[Category: Thermus thermophilus HB27]]
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[[Category: 2-aminoadipate transaminase]]
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[[Category: Fushinobu S]]
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[[Category: Thermus thermophilus]]
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[[Category: Kuzuyama T]]
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[[Category: Fushinobu, S.]]
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[[Category: Miyagawa T]]
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[[Category: Kuzuyama, T.]]
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[[Category: Miyazaki T]]
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[[Category: Miyagawa, T.]]
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[[Category: Nishiyama M]]
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[[Category: Miyazaki, T.]]
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[[Category: Tomita T]]
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[[Category: Nishiyama, M.]]
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[[Category: Tomita, T.]]
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[[Category: Alpha-aminoadipate aminotransferase]]
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[[Category: Substrate specificity]]
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[[Category: Thermus thermophilus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:42:39 2009''
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Current revision

Crystal structure of LysN, alpha-aminoadipate aminotransferase (substrate free form), from Thermus thermophilus HB27

PDB ID 2egy

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