2eja

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[[Image:2eja.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure Of Uroporphyrinogen Decarboxylase From Aquifex aeolicus==
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|PDB= 2eja |SIZE=350|CAPTION= <scene name='initialview01'>2eja</scene>, resolution 1.90&Aring;
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<StructureSection load='2eja' size='340' side='right'caption='[[2eja]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Act+Binding+Site+For+Residue+A+1209'>AC1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>
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<table><tr><td colspan='2'>[[2eja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EJA FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Uroporphyrinogen_decarboxylase Uroporphyrinogen decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.37 4.1.1.37] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eja OCA], [https://pdbe.org/2eja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eja RCSB], [https://www.ebi.ac.uk/pdbsum/2eja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eja ProSAT], [https://www.topsan.org/Proteins/RSGI/2eja TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eja OCA], [http://www.ebi.ac.uk/pdbsum/2eja PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eja RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/DCUP_AQUAE DCUP_AQUAE] Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity).
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== Evolutionary Conservation ==
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'''Crystal Structure Of Uroporphyrinogen Decarboxylase From Aquifex aeolicus'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2eja_consurf.spt"</scriptWhenChecked>
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2EJA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJA OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eja ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Uroporphyrinogen decarboxylase]]
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[[Category: Bagautdinov B]]
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[[Category: Bagautdinov, B.]]
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[[Category: Kunishima N]]
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[[Category: Kunishima, N.]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: dimer]]
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[[Category: lyase]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: nppsfa]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: uroporphyrinogen decarboxylase]]
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[[Category: x-ray diffraction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:49:58 2008''
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Current revision

Crystal Structure Of Uroporphyrinogen Decarboxylase From Aquifex aeolicus

PDB ID 2eja

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