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2eo8

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==Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus==
==Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus==
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<StructureSection load='2eo8' size='340' side='right' caption='[[2eo8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='2eo8' size='340' side='right'caption='[[2eo8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2eo8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EO8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2eo8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EO8 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyroglutamyl-peptidase_I Pyroglutamyl-peptidase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.3 3.4.19.3] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo8 OCA], [http://pdbe.org/2eo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eo8 RCSB], [http://www.ebi.ac.uk/pdbsum/2eo8 PDBsum], [http://www.topsan.org/Proteins/RSGI/2eo8 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo8 OCA], [https://pdbe.org/2eo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eo8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eo8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eo8 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PCP_PYRFU PCP_PYRFU]] Removes 5-oxoproline from various penultimate amino acid residues except L-proline.[HAMAP-Rule:MF_00417]
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[https://www.uniprot.org/uniprot/PCP_PYRFU PCP_PYRFU] Removes 5-oxoproline from various penultimate amino acid residues except L-proline.[HAMAP-Rule:MF_00417]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43587]]
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[[Category: Large Structures]]
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[[Category: Pyroglutamyl-peptidase I]]
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[[Category: Okazaki, N]]
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[[Category: Sakamoto, K]]
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[[Category: Yutani, K]]
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[[Category: Hydrolase]]
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[[Category: Pcp]]
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[[Category: Pgp-i]]
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[[Category: Protease]]
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Pyroglutamyl-peptidase i]]
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[[Category: Okazaki N]]
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[[Category: Sakamoto K]]
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[[Category: Yutani K]]

Current revision

Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus

PDB ID 2eo8

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