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2hjw

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[[Image:2hjw.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the BC domain of ACC2==
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|PDB= 2hjw |SIZE=350|CAPTION= <scene name='initialview01'>2hjw</scene>, resolution 2.50&Aring;
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<StructureSection load='2hjw' size='340' side='right'caption='[[2hjw]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2hjw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HJW FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Acetyl-CoA_carboxylase Acetyl-CoA carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.2 6.4.1.2]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE= ACACB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hjw OCA], [https://pdbe.org/2hjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hjw RCSB], [https://www.ebi.ac.uk/pdbsum/2hjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hjw ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACACB_HUMAN ACACB_HUMAN] ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/2hjw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hjw ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of the BC domain of ACC2'''
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==See Also==
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*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2HJW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJW OCA].
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[[Category: Acetyl-CoA carboxylase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Cho, Y S.]]
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[[Category: Cho YS]]
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[[Category: Heo, Y S.]]
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[[Category: Heo YS]]
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[[Category: Kim, H T.]]
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[[Category: Kim HT]]
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[[Category: Lee, J I.]]
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[[Category: Lee JI]]
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[[Category: Lee, T G.]]
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[[Category: Lee TG]]
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[[Category: Shin, D.]]
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[[Category: Shin D]]
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[[Category: bc domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:17:57 2008''
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Current revision

Crystal Structure of the BC domain of ACC2

PDB ID 2hjw

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