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2hrb
From Proteopedia
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<StructureSection load='2hrb' size='340' side='right'caption='[[2hrb]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2hrb' size='340' side='right'caption='[[2hrb]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2hrb]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2hrb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HRB FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hrb OCA], [https://pdbe.org/2hrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hrb RCSB], [https://www.ebi.ac.uk/pdbsum/2hrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hrb ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CBR3_HUMAN CBR3_HUMAN] Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).<ref>PMID:18493841</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Pilka | + | [[Category: Pilka ES]] |
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Current revision
Crystal Structure of human Carbonyl Reductase 3, complexed with NADP+
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