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2pcl

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==Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5==
==Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5==
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<StructureSection load='2pcl' size='340' side='right' caption='[[2pcl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='2pcl' size='340' side='right'caption='[[2pcl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pcl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PCL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pcl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2pcj|2pcj]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pcl RCSB], [http://www.ebi.ac.uk/pdbsum/2pcl PDBsum], [http://www.topsan.org/Proteins/RSGI/2pcl TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcl OCA], [https://pdbe.org/2pcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcl RCSB], [https://www.ebi.ac.uk/pdbsum/2pcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcl ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcl TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LOLD_AQUAE LOLD_AQUAE]] Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity).
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[https://www.uniprot.org/uniprot/LOLD_AQUAE LOLD_AQUAE] Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcl_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcl_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcl ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ABC transporter|ABC transporter]]
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aquifex aeolicus]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Ebihara, A]]
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[[Category: Large Structures]]
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[[Category: Jeyakanthan, J]]
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[[Category: Ebihara A]]
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[[Category: Kanaujia, S P]]
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[[Category: Jeyakanthan J]]
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[[Category: Kuramitsu, S]]
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[[Category: Kanaujia SP]]
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[[Category: Nakagawa, N]]
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[[Category: Kuramitsu S]]
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[[Category: Structural genomic]]
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[[Category: Nakagawa N]]
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[[Category: Rafi, Z A]]
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[[Category: Rafi ZA]]
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[[Category: Sekar, K]]
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[[Category: Sekar K]]
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[[Category: Shinkai, A]]
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[[Category: Shinkai A]]
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[[Category: Shiro, Y]]
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[[Category: Shiro Y]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Abc transporter]]
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[[Category: Atp-binding protein]]
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[[Category: Hydrolase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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Current revision

Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5

PDB ID 2pcl

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