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2yr1
From Proteopedia
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==Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426== | ==Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426== | ||
| - | <StructureSection load='2yr1' size='340' side='right' caption='[[2yr1]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='2yr1' size='340' side='right'caption='[[2yr1]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yr1]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2yr1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_kaustophilus_HTA426 Geobacillus kaustophilus HTA426]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YR1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yr1 OCA], [https://pdbe.org/2yr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yr1 RCSB], [https://www.ebi.ac.uk/pdbsum/2yr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yr1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yr1 TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AROD_GEOKA AROD_GEOKA] Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.[HAMAP-Rule:MF_00214] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yr/2yr1_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yr/2yr1_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yr1 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Dehydroquinase|Dehydroquinase]] | + | *[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Geobacillus kaustophilus HTA426]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bessho | + | [[Category: Bessho Y]] |
| - | [[Category: Chen | + | [[Category: Chen L]] |
| - | [[Category: Chrzas | + | [[Category: Chrzas J]] |
| - | [[Category: Fu | + | [[Category: Fu ZQ]] |
| - | [[Category: Kagawa | + | [[Category: Kagawa W]] |
| - | [[Category: Kurumizaka | + | [[Category: Kurumizaka H]] |
| - | + | [[Category: Wang BC]] | |
| - | [[Category: Wang | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426
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