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8bhm
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==GABA-A receptor a5 homomer - a5V3 - DMCM== | |
| - | + | <StructureSection load='8bhm' size='340' side='right'caption='[[8bhm]], [[Resolution|resolution]] 2.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8bhm]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BHM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.95Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=R63:methyl+4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate'>R63</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bhm OCA], [https://pdbe.org/8bhm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bhm RCSB], [https://www.ebi.ac.uk/pdbsum/8bhm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bhm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GBRA5_HUMAN GBRA5_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chirgadze DY]] | ||
| + | [[Category: Hardwick SW]] | ||
| + | [[Category: Malinauskas TM]] | ||
| + | [[Category: Miller PS]] | ||
Current revision
GABA-A receptor a5 homomer - a5V3 - DMCM
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