This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2z1b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:18, 1 November 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2z1b.png|left|200px]]
 
-
{{STRUCTURE_2z1b| PDB=2z1b | SCENE= }}
+
==Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs==
-
 
+
<StructureSection load='2z1b' size='340' side='right'caption='[[2z1b]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
-
===Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2z1b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1B FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1b OCA], [https://pdbe.org/2z1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1b RCSB], [https://www.ebi.ac.uk/pdbsum/2z1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1b ProSAT], [https://www.topsan.org/Proteins/RSGI/2z1b TOPSAN]</span></td></tr>
-
[[2z1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1B OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HEM2_MOUSE HEM2_MOUSE] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1b_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1b ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
*[[Porphobilinogen synthase|Porphobilinogen synthase]]
*[[Porphobilinogen synthase|Porphobilinogen synthase]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Porphobilinogen synthase]]
+
[[Category: Kawazoe M]]
-
[[Category: Kawazoe, M.]]
+
[[Category: Kishishita S]]
-
[[Category: Kishishita, S.]]
+
[[Category: Murayama K]]
-
[[Category: Murayama, K.]]
+
[[Category: Shirozu M]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Takemoto C]]
-
[[Category: Shirozu, M.]]
+
[[Category: Terada T]]
-
[[Category: Takemoto, C.]]
+
[[Category: Wang H]]
-
[[Category: Terada, T.]]
+
[[Category: Xie Y]]
-
[[Category: Wang, H.]]
+
[[Category: Yokoyama S]]
-
[[Category: Xie, Y.]]
+
-
[[Category: Yokoyama, S.]]
+
-
[[Category: Conserved hypothetical protein]]
+
-
[[Category: Lyase]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Porphyrin biosynthesis]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structure genomic]]
+

Current revision

Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs

PDB ID 2z1b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2z1b"
Personal tools