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2z1b
From Proteopedia
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==Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs== | ==Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs== | ||
| - | <StructureSection load='2z1b' size='340' side='right' caption='[[2z1b]], [[Resolution|resolution]] 3.30Å' scene=''> | + | <StructureSection load='2z1b' size='340' side='right'caption='[[2z1b]], [[Resolution|resolution]] 3.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2z1b]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2z1b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1B FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1b OCA], [https://pdbe.org/2z1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1b RCSB], [https://www.ebi.ac.uk/pdbsum/2z1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1b ProSAT], [https://www.topsan.org/Proteins/RSGI/2z1b TOPSAN]</span></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </table> |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/HEM2_MOUSE HEM2_MOUSE] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1b_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1b_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1b ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Kawazoe M]] | |
| - | [[Category: Kawazoe | + | [[Category: Kishishita S]] |
| - | [[Category: Kishishita | + | [[Category: Murayama K]] |
| - | [[Category: Murayama | + | [[Category: Shirozu M]] |
| - | + | [[Category: Takemoto C]] | |
| - | [[Category: Shirozu | + | [[Category: Terada T]] |
| - | [[Category: Takemoto | + | [[Category: Wang H]] |
| - | [[Category: Terada | + | [[Category: Xie Y]] |
| - | [[Category: Wang | + | [[Category: Yokoyama S]] |
| - | [[Category: Xie | + | |
| - | [[Category: Yokoyama | + | |
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Current revision
Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs
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Categories: Large Structures | Mus musculus | Kawazoe M | Kishishita S | Murayama K | Shirozu M | Takemoto C | Terada T | Wang H | Xie Y | Yokoyama S
