2z6b

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<StructureSection load='2z6b' size='340' side='right'caption='[[2z6b]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
<StructureSection load='2z6b' size='340' side='right'caption='[[2z6b]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z6B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z6B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NEN:1-ETHYL-PYRROLIDINE-2,5-DIONE'>NEN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4]), 27 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NEN:1-ETHYL-PYRROLIDINE-2,5-DIONE'>NEN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z6b OCA], [https://pdbe.org/2z6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z6b RCSB], [https://www.ebi.ac.uk/pdbsum/2z6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z6b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z6b OCA], [https://pdbe.org/2z6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z6b RCSB], [https://www.ebi.ac.uk/pdbsum/2z6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z6b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VG05_BPT4 VG05_BPT4]] Tail-associated lysozyme essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. [[https://www.uniprot.org/uniprot/VG27_BPT4 VG27_BPT4]] Structural component of the baseplate.
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[https://www.uniprot.org/uniprot/NEEDL_BPT4 NEEDL_BPT4] Tail-associated lysozyme of the baseplate hub that is essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. Involved in the tail assembly.<ref>PMID:12837775</ref> <ref>PMID:21129200</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpt4]]
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[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Arisaka F]]
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[[Category: Arisaka, F]]
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[[Category: Kanamaru S]]
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[[Category: Kanamaru, S]]
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[[Category: Koshiyama T]]
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[[Category: Koshiyama, T]]
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[[Category: Nagano S]]
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[[Category: Nagano, S]]
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[[Category: Shiro Y]]
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[[Category: Shiro, Y]]
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[[Category: Ueno T]]
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[[Category: Ueno, T]]
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[[Category: Watanabe Y]]
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[[Category: Watanabe, Y]]
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[[Category: Yokoi N]]
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[[Category: Yokoi, N]]
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[[Category: Antimicrobial]]
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[[Category: Bacteriolytic enzyme]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-structural protein complex]]
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[[Category: Late protein]]
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[[Category: Protein containing metal complex]]
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[[Category: Virion]]
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Revision as of 13:23, 1 November 2023

Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin

PDB ID 2z6b

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