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2z9u

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==Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution==
==Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution==
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<StructureSection load='2z9u' size='340' side='right' caption='[[2z9u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2z9u' size='340' side='right'caption='[[2z9u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z9u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33669 Atcc 33669]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z9U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z9u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z9U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2z9v|2z9v]], [[2z9w|2z9w]], [[2z9x|2z9x]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mlr6806 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=381 ATCC 33669])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z9u OCA], [https://pdbe.org/2z9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z9u RCSB], [https://www.ebi.ac.uk/pdbsum/2z9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z9u ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyridoxamine--pyruvate_transaminase Pyridoxamine--pyruvate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.30 2.6.1.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z9u OCA], [http://pdbe.org/2z9u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z9u RCSB], [http://www.ebi.ac.uk/pdbsum/2z9u PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PPAT_RHILO PPAT_RHILO] Catalyzes a reversible transamination reaction between pyridoxamine and pyruvate to form pyridoxal and L-alanine.<ref>PMID:16545075</ref> <ref>PMID:17989071</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/2z9u_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/2z9u_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Aspartate Aminotransferase|Aspartate Aminotransferase]]
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*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 33669]]
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[[Category: Large Structures]]
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[[Category: Pyridoxamine--pyruvate transaminase]]
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[[Category: Mesorhizobium loti]]
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[[Category: Hayashi, H]]
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[[Category: Hayashi H]]
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[[Category: Mikami, B]]
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[[Category: Mikami B]]
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[[Category: Mizutani, K]]
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[[Category: Mizutani K]]
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[[Category: Ohnishi, K]]
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[[Category: Ohnishi K]]
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[[Category: Yagi, T]]
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[[Category: Yagi T]]
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[[Category: Yamasaki, M]]
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[[Category: Yamasaki M]]
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[[Category: Yokochi, N]]
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[[Category: Yokochi N]]
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[[Category: Yoshikane, Y]]
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[[Category: Yoshikane Y]]
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[[Category: Aminotransferase]]
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[[Category: Pyridoxamine]]
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[[Category: Pyruvate]]
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[[Category: Transferase]]
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Current revision

Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution

PDB ID 2z9u

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