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2zax

From Proteopedia

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[[Image:2zax.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of Ferric Cytochrome P450cam==
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|PDB= 2zax |SIZE=350|CAPTION= <scene name='initialview01'>2zax</scene>, resolution 1.60&Aring;
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<StructureSection load='2zax' size='340' side='right'caption='[[2zax]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=CAM:CAMPHOR'>CAM</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
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<table><tr><td colspan='2'>[[2zax]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZAX FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Camphor_5-monooxygenase Camphor 5-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.1 1.14.15.1]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= camC, cyp101 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAM:CAMPHOR'>CAM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zax OCA], [https://pdbe.org/2zax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zax RCSB], [https://www.ebi.ac.uk/pdbsum/2zax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zax ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPXA_PSEPU CPXA_PSEPU] Involved in a camphor oxidation system.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/2zax_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zax ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of Ferric Cytochrome P450cam'''
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==See Also==
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2ZAX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAX OCA].
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[[Category: Large Structures]]
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==Reference==
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Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam., Harada K, Sakurai K, Ikemura K, Ogura T, Hirota S, Shimada H, Hayashi T, J Am Chem Soc. 2008 Jan 16;130(2):432-3. Epub 2007 Dec 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18088124 18088124]
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[[Category: Camphor 5-monooxygenase]]
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[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
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[[Category: Single protein]]
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[[Category: Harada K]]
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[[Category: Harada, K.]]
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[[Category: Hayashi T]]
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[[Category: Hayashi, T.]]
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[[Category: Sakurai K]]
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[[Category: Sakurai, K.]]
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[[Category: Shimada H]]
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[[Category: Shimada, H.]]
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[[Category: Tsukihara T]]
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[[Category: Tsukihara, T.]]
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[[Category: CAM]]
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[[Category: HEM]]
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[[Category: K]]
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[[Category: TRS]]
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[[Category: camphor-hydroxylase]]
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[[Category: heme]]
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[[Category: iron]]
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[[Category: membrane]]
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[[Category: metal-binding]]
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[[Category: monooxygenase]]
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[[Category: oxidoreductase]]
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[[Category: p450cam]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:53:25 2008''
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Current revision

Crystal Structure of Ferric Cytochrome P450cam

PDB ID 2zax

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