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2zpk
From Proteopedia
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==Crystal structure of P20.1 Fab fragment in complex with its antigen peptide== | ==Crystal structure of P20.1 Fab fragment in complex with its antigen peptide== | ||
| - | <StructureSection load='2zpk' size='340' side='right' caption='[[2zpk]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='2zpk' size='340' side='right'caption='[[2zpk]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2zpk]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2zpk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZPK FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpk OCA], [https://pdbe.org/2zpk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zpk RCSB], [https://www.ebi.ac.uk/pdbsum/2zpk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpk ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PAR4_HUMAN PAR4_HUMAN] Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.<ref>PMID:10079109</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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*[[Antibody 3D structures|Antibody 3D structures]] | *[[Antibody 3D structures|Antibody 3D structures]] | ||
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
| + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Nogi | + | [[Category: Nogi T]] |
| - | [[Category: Sanagawa | + | [[Category: Sanagawa T]] |
| - | [[Category: Takagi | + | [[Category: Takagi J]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of P20.1 Fab fragment in complex with its antigen peptide
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