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2zqc

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Aztreonam acyl-intermediate structure of class a beta-lactam Toho-1 E166A/R274N/R276N triple mutant

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Retrieved from "http://52.214.119.220/wiki/index.php/2zqc"

@@ Line 1: / Line 1: @@
 ==Aztreonam acyl-intermediate structure of class a beta-lactam Toho-1 E166A/R274N/R276N triple mutant==
-<StructureSection load='2zqc' size='340' side='right' caption='[[2zqc]], [[Resolution|resolution]] 1.07&Aring;' scene=''>
+<StructureSection load='2zqc' size='340' side='right'caption='[[2zqc]], [[Resolution|resolution]] 1.07&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2zqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQC FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2zqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQC FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZR:2-({[(1Z)-1-(2-AMINO-1,3-THIAZOL-4-YL)-2-OXO-2-{[(2S,3S)-1-OXO-3-(SULFOAMINO)BUTAN-2-YL]AMINO}ETHYLIDENE]AMINO}OXY)-2-METHYLPROPANOIC+ACID'>AZR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.07&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zq7|2zq7]], [[2zq8|2zq8]], [[2zq9|2zq9]], [[2zqa|2zqa]], [[2zqd|2zqd]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZR:2-({[(1Z)-1-(2-AMINO-1,3-THIAZOL-4-YL)-2-OXO-2-{[(2S,3S)-1-OXO-3-(SULFOAMINO)BUTAN-2-YL]AMINO}ETHYLIDENE]AMINO}OXY)-2-METHYLPROPANOIC+ACID'>AZR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqc OCA], [https://pdbe.org/2zqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqc RCSB], [https://www.ebi.ac.uk/pdbsum/2zqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqc ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqc OCA], [http://pdbe.org/2zqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zqc RCSB], [http://www.ebi.ac.uk/pdbsum/2zqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqc ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity.
+[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 24: / Line 22: @@
 ==See Also==
-*[[Beta-lactamase|Beta-lactamase]]
+*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: Bacillus coli migula 1895]]
+[[Category: Escherichia coli]]
-[[Category: Beta-lactamase]]
+[[Category: Large Structures]]
-[[Category: Ishii, Y]]
+[[Category: Ishii Y]]
-[[Category: Matsuzawa, H]]
+[[Category: Matsuzawa H]]
-[[Category: Miyano, M]]
+[[Category: Miyano M]]
-[[Category: Nitanai, Y]]
+[[Category: Nitanai Y]]
-[[Category: Shimamura, T]]
+[[Category: Shimamura T]]
-[[Category: Takehira, M]]
+[[Category: Takehira M]]
-[[Category: Uchiyama, T]]
+[[Category: Uchiyama T]]
-[[Category: Yutani, K]]
+[[Category: Yutani K]]
-[[Category: Acyl-enzyme complex]]
-[[Category: Antibiotic resistance]]
-[[Category: Aztreonam]]
-[[Category: Esbl]]
-[[Category: Extended-spectrum]]
-[[Category: Hydrolase]]
-[[Category: Toho-1]]

2zqc

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Aztreonam acyl-intermediate structure of class a beta-lactam Toho-1 E166A/R274N/R276N triple mutant

Structural highlights

Function

Evolutionary Conservation

See Also

Contents

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