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2zuc

From Proteopedia

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==Crystal structure of left-handed RadA filament==
==Crystal structure of left-handed RadA filament==
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<StructureSection load='2zuc' size='340' side='right' caption='[[2zuc]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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<StructureSection load='2zuc' size='340' side='right'caption='[[2zuc]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zuc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zuc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZUC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dfl|2dfl]], [[2zub|2zub]], [[2zud|2zud]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rada ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zuc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuc OCA], [https://pdbe.org/2zuc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zuc RCSB], [https://www.ebi.ac.uk/pdbsum/2zuc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuc ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zuc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zuc RCSB], [http://www.ebi.ac.uk/pdbsum/2zuc PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/RADA_SACS2 RADA_SACS2] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zuc_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zuc_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zuc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2zuc" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Resolvase|Resolvase]]
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*[[Resolvase 3D structures|Resolvase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Sulfolobus solfataricus]]
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[[Category: Large Structures]]
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[[Category: Chang, Y W.]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Ko, T P.]]
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[[Category: Chang YW]]
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[[Category: Wang, A H.J.]]
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[[Category: Ko TP]]
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[[Category: Wang, T F.]]
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[[Category: Wang AHJ]]
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[[Category: Archaea]]
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[[Category: Wang TF]]
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[[Category: Atp-binding]]
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[[Category: Dmc1]]
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[[Category: Dna binding]]
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[[Category: Dna damage]]
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[[Category: Dna recombination]]
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[[Category: Dna-binding]]
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[[Category: Filament]]
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[[Category: Left-handed]]
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[[Category: Molecular switch]]
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[[Category: Nucleotide-binding]]
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[[Category: Rad51]]
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[[Category: Reca]]
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[[Category: Recombination]]
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Current revision

Crystal structure of left-handed RadA filament

PDB ID 2zuc

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